An AAV capsid reprogrammed to bind human Transferrin Receptor mediates brain-wide gene delivery.
Huang Q, Chan KY, Lou S, Keyes C, Wu J, Botticello-Romero NR, Zheng Q, Johnston J, Mills A, Brauer PP, Clouse G, Pacouret S, Harvey JW, Beddow T, Hurley JK, Tobey IG, Powell M, Chen AT, Barry AJ, Eid FE, Chan YA, Deverman BE
bioRxiv [Preprint]. 2023 Dec 22:2023.12.20.572615. doi: 10.1101/2023.12.20.572615.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 218793 | pAAV-CAG-SV40NLSf-mScarletP2A-hLuc | AAV reporter genome plasmid |
| 218794 | pAAV-CMV-CBA-hGBA1-HA-hGHpA | AAV reporter genome plasmid |
| 218795 | pAAV-CMV-CBA-hGBA1-cm-hGBA1-hGHpA | AAV reporter genome plasmid |
| 218796 | kiCAP-AAV-BI-hTFR1 | RepCap for AAV production |
| 218797 | kiCAP-AAV-BI-hTFR1-2 | RepCap for AAV production |
| 218798 | kiCAP-AAV-BI-hTFR1-3 | RepCap for AAV production |
| 218799 | kiCAP-AAV-BI-hTFR1-4 | RepCap for AAV production |