RUNX3 inactivates oncogenic MYC through disruption of MYC/MAX complex and subsequent recruitment of GSK3beta-FBXW7 cascade.
Oei V, Chuang LSH, Matsuo J, Srivastava S, Teh M, Ito Y
Commun Biol. 2023 Jul 3;6(1):689. doi: 10.1038/s42003-023-05037-0. PubMed Article
Oei V, Chuang LSH, Matsuo J, Srivastava S, Teh M, Ito Y
Commun Biol. 2023 Jul 3;6(1):689. doi: 10.1038/s42003-023-05037-0. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 203424 | pCbs Flag CMYC (bHLH/LZ) | Mammalian expression of MYC |
| 203425 | pCDNA3-HA-HA-human CMYC (116-439) | Mammalian expression of MYC |
| 203426 | pCDNA3-HA-HA-human CMYC (1-170) | Mammalian expression of MYC |
| 203427 | pCDNA3-HA-HA-human CMYC (1-208) | Mammalian expression of MYC |
| 203428 | pCDNA3-HA-HA-human CMYC (1-277) | Mammalian expression of MYC |
| 203429 | pCDNA3-HA-HA-human CMYC (1-357) | Mammalian expression of MYC |
| 203430 | pCDNA3-HA-HA-human CMYC (170-439) | Mammalian expression of MYC |
| 203431 | pCDNA3-HA-HA-human CMYC (201-298) | Mammalian expression of MYC |
| 203432 | pCDNA3-HA-HA-human CMYC (208-300) | Mammalian expression of MYC |
| 203433 | pCDNA3-HA-HA-human CMYC (208-439) | Mammalian expression of MYC |
| 203434 | pCDNA3-HA-HA-human CMYC (277-357) | Mammalian expression of MYC |
| 203435 | pCDNA3-HA-HA-human CMYC (277-439) | Mammalian expression of MYC |
| 203436 | pCDNA3-HA-HA-human CMYC S62A | Mammalian expression of MYC |
| 203437 | pCDNA3-HA-HA-human CMYC S62D | Mammalian expression of MYC |
| 203438 | pcFLAG RUNX3 (R122C) | Mammalian expression of RUNX3 |
| 203439 | pRetroX-Tight-puro-3xFLAG-RUNX3 R122C | Mammalian expression of RUNX4 |
| 203440 | pGEX4T-1-RUNX3 aa 49-187 | Bacterial expression of RUNX5 |