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Massively parallel base editing to map variant effects in human hematopoiesis.

Martin-Rufino JD, Castano N, Pang M, Grody EI, Joubran S, Caulier A, Wahlster L, Li T, Qiu X, Riera-Escandell AM, Newby GA, Al'Khafaji A, Chaudhary S, Black S, Weng C, Munson G, Liu DR, Wlodarski MW, Sims K, Oakley JH, Fasano RM, Xavier RJ, Lander ES, Klein DE, Sankaran VG
Cell. 2023 Apr 27:S0092-8674(23)00332-X. doi: 10.1016/j.cell.2023.03.035. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
203321pCROPseq-VEX-optimized-scaffoldModified CROPseq vector for efficient CRISPR screens in hematopoiesis
203328ABE8e-Cas9NGPlasmid for bacterial purification of codon optimized ABE8e-Cas9NG
203329evoFERNY-Cas9NGPlasmid for bacterial purification of codon optimized evoFERNY-Cas9NG

Antibodies from Article