YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis.
Wu BK, Mei SC, Chen EH, Zheng Y, Pan D
Nat Genet. 2022 Aug;54(8):1202-1213. doi: 10.1038/s41588-022-01119-7. Epub 2022 Jul 14.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 235692 | pGL3-Cyr61-rDMR | Measure the activity of the reduced differentially methylated region (rDMR) of Cyr61 with luciferase assay |
| 235693 | pGL3-Cyr61-rDMRdeltaTEAD | Measure the activity of the reduced differentially methylated region (rDMR) of Cyr61 lacking Tead-binding motif with luciferase assay |
| 235694 | pGL3-Myc-rDMR | Measure the activity of the reduced differentially methylated region (rDMR) of Myc with luciferase assay |
| 235696 | pGL3-Ctgf-rDMR | Measure the activity of the reduced differentially methylated region (rDMR) of Ctgf with luciferase assay |
| 235697 | pGL3-Ctgf-rDMRdeltaTEAD | Measure the activity of the reduced differentially methylated region (rDMR) of Ctgf lacking Tead-binding motif with luciferase assay |