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Human STING is a proton channel.

Liu B, Carlson RJ, Pires IS, Gentili M, Feng E, Hellier Q, Schwartz MA, Blainey PC, Irvine DJ, Hacohen N
Science. 2023 Aug 4;381(6657):508-514. doi: 10.1126/science.adf8974. Epub 2023 Aug 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
200937MGAT-SEP-mRuby3cis/medial golgi localized pH sensor using sensorsuperecliptic pHluorin (SEP) and mRuby3
200938GALT-SEP-mRuby3trans-Golgi localized pH sensor using sensorsuperecliptic pHluorin (SEP) and mRuby3
200939LAMP1-SEP-mRuby3endolysosome localized pH sensor using sensorsuperecliptic pHluorin (SEP) and mRuby3
200940STING-miRFP680STING fused with miRFP680 for live cell imaging
200942NLRP3-mNeonGreenNLRP3 fused with mNeonGreen to indicate its localization change
200943RFP-LC3BRFP fused with LC3B for reporting LC3B lipidation

Antibodies from Article