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Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.

Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nat Commun. 2022 Nov 17;13(1):7031. doi: 10.1038/s41467-022-34850-0. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
211921mito-EcSTHMitochondrial localization of EcSTH
211922mito-EcSTH-LbNOXMitochondrial localization of EcSTH-LbNOX
211923EcSTHThis plasmid contains human codon optimized sequence of EcSTH which can be used to increase NADH/NAD ratio and decrease NADPH/NADP ratio in mammalian cells.
211924EcSTH-LbNOXThis plasmid contains human codon optimized sequence of EcSTH-LbNOX which can be used to decrease NADPH/NADP ratio in mammalian cells.

Antibodies from Article