Engineered PROTAC-CID Systems for Mammalian Inducible Gene Regulation.
Ma D, Yuan Q, Peng F, Paredes V, Zeng H, Osikpa EC, Yang Q, Peddi A, Patel A, Liu MS, Sun Z, Gao X
J Am Chem Soc. 2023 Jan 25;145(3):1593-1606. doi: 10.1021/jacs.2c09129. Epub 2023 Jan 10.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 200434 | PC1-29-9-2_GAL4-VHL | Expresses the GAL4 DNA Binding domain linked to the VHL E3 Ubiquitin Ligase |
| 200435 | PC15-421-14-1_TRIM24-BD-VPR | Expresses the VPR transactivation domain linked to the TRIM24(BD) target protein |
| 200436 | PC17-605-9-1_BRD4-BD2-VPR | Expresses the VPR transactivation domain linked to the BRD4(BD2) target protein |
| 200437 | PC7-709-28-1_CRBN-VPR | Expresses the VPR transactivation domain linked to the CRBN E3 Ubiquitin Ligase |
| 200438 | PC3-709-33-10_GAL4-FKBP12(F36V) | Expresses the GAL4 DNA Binding domain linked to the FKBP12(F36V) target protein |