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Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on "toxin sponge" proteins.

Abderemane-Ali F, Rossen ND, Kobiela ME, Craig RA, Garrison CE, Chen Z, Colleran CM, O'Connell LA, Du Bois J, Dumbacher JP, Minor DL
J Gen Physiol. 2021 Sep 6;153(9):e202112872. doi: 10.1085/jgp.202112872. Epub 2021 Aug 5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
200230Pum NaV1.4Expression in mammalian cells or oocytes
200231Pum NaVB2Expression in mammalian cells or oocytes
200232Pum NaV1.5Expression in mammalian cells or oocytes
200233Pt NaV1.4Expression in mammalian cells or oocytes
200250Dt NaV1.4Expression in mammalian cells or oocytes
200284Pum NaV1.4-N432TExpression in mammalian cells or oocytes
200285Pum NaV1.4-N830TExpression in mammalian cells or oocytes
200286Pum NaV1.4-N11306TExpression in mammalian cells or oocytes
200287Pum NaV1.4-N1609TExpression in mammalian cells or oocytes
200288Pum NaV1.4-N1609AExpression in mammalian cells or oocytes
200289Pt NaV1.4-N1600TExpression in mammalian cells or oocytes
200308Dt NaV1.4-N1600TExpression in mammalian cells or oocytes

Antibodies from Article