A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Antiapoptotic Protein in Kidney Cancer.
Grubb T, Maganti S, Krill-Burger JM, Fraser C, Stransky L, Radivoyevitch T, Sarosiek KA, Vazquez F, Kaelin WG, Chakraborty AA
Clin Cancer Res. 2022 Nov 1;28(21):4689-4701. doi: 10.1158/1078-0432.CCR-22-0669.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 203573 | pLX304-BCL-XL-Y195F | Expresses V5-tagged BCL-XL with partial drug resistance to A-1331852 in mammalian cells. |
| 203574 | pLX304-BCL-XL-499R | Expresses V5-tagged BCL-XL with resistance to shRNA (TRCN0000033499) in mammalian cells. |
| 203575 | pLX304-BCL-XL-499/500R | Expresses V5-tagged BCL-XL with resistance to shRNA (TRCN0000033499, TRCN0000033500) in mammalian cells. |