Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design.
Ogden PJ, Kelsic ED, Sinai S, Church GM
Science. 2019 Nov 29;366(6469):1139-1143. doi: 10.1126/science.aaw2900.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 199599 | pRep | Expresses AAV2 rep gene; accessory plasmid for the pCMV-Cap SSM library. |
| 199601 | pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library | pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter |