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Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration.

De Pace R, Ghosh S, Ryan VH, Sohn M, Jarnik M, Rezvan Sangsari P, Morgan NY, Dale RK, Ward ME, Bonifacino JS
Nat Neurosci. 2024 Apr 10. doi: 10.1038/s41593-024-01619-1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
198337PB-Ef1a-PP7 coat protein-Halo-GB1x3-WPREPB plasmid expressing Halo-tagged PP7 coat protein
198338PB-Ef1a-SunTag-RPS7-PP7-WPREPB plasmid expressing RPS7 mRNA tagged with SunTag repeats and PP7 stem loops
198339PB-Ef1a-RPS27A-UTR-PP7-WPREPB plasmid expressing RPS27A with its 3'UTR tagged to PP7 stem loops

Antibodies from Article