Heterogeneous beta-catenin activation is sufficient to cause hepatocellular carcinoma in zebrafish.
Kalasekar SM, Kotiyal S, Conley C, Phan C, Young A, Evason KJ
Biol Open. 2019 Oct 17;8(10):bio047829. doi: 10.1242/bio.047829.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 198240 | pKE12-ISceI-fabp10a:loxP-BFP-loxP-Xla.Ctnnb1 | For I-SceI-mediated transgenesis in zebrafish; fabp10a promoter drives expression of activated β-catenin preceded by a blue fluorescent protein (BFP)-STOP cassette flanked by loxP sites |
| 198242 | pKE13-ISceI-fabp10a:CreERT2 | For I-SceI-mediated transgenesis in zebrafish; fabp10a promoter driving tamoxifen-inducible Cre recombinase |