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An AAV capsid increases transduction of striatum and a ChAT promoter allows selective cholinergic neuron transduction.

Santoscoy MC, Espinoza P, De La Cruz D, Mahamdeh M, Starr JR, Patel N, Maguire CA
Mol Ther Methods Clin Dev. 2023 May 9;29:532-540. doi: 10.1016/j.omtm.2023.05.001. eCollection 2023 Jun 8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
197564pAAV-hChATp-tdTomatoExpresses tdTomato under a human choline acetyltransferase (hChAT) promoter fragment

Antibodies from Article