An AAV capsid increases transduction of striatum and a ChAT promoter allows selective cholinergic neuron transduction.
Santoscoy MC, Espinoza P, De La Cruz D, Mahamdeh M, Starr JR, Patel N, Maguire CA
Mol Ther Methods Clin Dev. 2023 May 9;29:532-540. doi: 10.1016/j.omtm.2023.05.001. eCollection 2023 Jun 8.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
197564 | pAAV-hChATp-tdTomato | Expresses tdTomato under a human choline acetyltransferase (hChAT) promoter fragment |