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iPSC motor neurons, but not other derived cell types, capture gene expression changes in postmortem sporadic ALS motor neurons.

Held A, Adler M, Marques C, Reyes CJ, Kavuturu AS, Quadros ARAA, Ndayambaje IS, Lara E, Ward M, Lagier-Tourenne C, Wainger BJ
Cell Rep. 2023 Aug 30;42(9):113046. doi: 10.1016/j.celrep.2023.113046. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
197089PB-tetO-hNILPiggyBac plasmid with tet-inducible expression of transcription factors for motor neuron differentiation
197090PB-tetO-NGN2PiggyBac plasmid with tet-inducible expression of transcription factors for cortical neuron differentiation
197092PB-tetO-NBPiggyBac plasmid with tet-inducible expression of transcription factors for sensory neuron differentiation

Antibodies from Article