Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS.
Stanton AC, Lagerborg KA, Tellez L, Krunnfusz A, King EM, Ye S, Solomon IH, Tabebordbar M, Sabeti PC
Med (N Y). 2022 Nov 15:S2666-6340(22)00456-1. doi: 10.1016/j.medj.2022.11.002.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 196679 | kiCAP-AAV-MDV1A | Rep/Cap plasmid for the production of MDV1A, an AAV capsid with CNS tropism in mice. |
| 196680 | kiCAP-AAV-MDV1B | Rep/Cap plasmid for the production of MDV1B, an AAV capsid with CNS tropism in mice. |
| 196681 | kiCAP-AAV-M.Mus.1 | Rep/Cap plasmid for the production of M.Mus.1, an AAV capsid with CNS tropism in mice. |
| 196682 | kiCAP-AAV-M.Mus.2 | Rep/Cap plasmid for the production of M.Mus.2, an AAV capsid with CNS tropism in mice. |
| 196683 | kiCAP-AAV-PAL1A | Rep/Cap plasmid for the production of PAL1A, an AAV capsid with CNS tropism in macaques. |
| 196684 | kiCAP-AAV-PAL1B | Rep/Cap plasmid for the production of PAL1B, an AAV capsid with CNS tropism in macaques. |
| 196685 | kiCAP-AAV-PAL1C | Rep/Cap plasmid for the production of PAL1C, an AAV capsid with CNS tropism in macaques. |
| 196686 | kiCAP-AAV-PAL1D | Rep/Cap plasmid for the production of PAL1D, an AAV capsid with CNS tropism in macaques. |
| 196687 | kiCAP-AAV-M.Fas.1 | Rep/Cap plasmid for the production of M.Fas.1, an AAV capsid with CNS tropism in macaques. |
| 196688 | kiCAP-AAV-M.Fas.2 | Rep/Cap plasmid for the production of M.Fas.2, an AAV capsid with CNS tropism in macaques. |
| 196689 | kiCAP-AAV-M.Fas.3 | Rep/Cap plasmid for the production of M.Fas.3, an AAV capsid with CNS tropism in macaques. |
| 196690 | kiCAP-AAV-M.Fas.4 | Rep/Cap plasmid for the production of M.Fas.4, an AAV capsid with CNS tropism in macaques. |
| 196691 | kiCAP-AAV-PAL2 | Rep/Cap plasmid for the production of PAL2, an AAV capsid with CNS tropism in macaques. |