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Tail-Engineered Phage P2 Enables Delivery of Antimicrobials into Multiple Gut Pathogens.

Fa-Arun J, Huan YW, Darmon E, Wang B
ACS Synth Biol. 2023 Feb 17;12(2):596-607. doi: 10.1021/acssynbio.2c00615. Epub 2023 Feb 2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
196332pP2_tail_fiber Plasmid expressing P2 tail fiber H and chaperone protein G
196333pP2-phiV10Plasmid expressing chimeric P2-phiV10 tail fiber
196334pP2-P1(S')Plasmid expressing chimeric P2-P1(S') tail fiber
196335P4 cosmidP4 cosmid with CRISPR-Cas9 system
197132∆cosσε ∆HGDeficient in the packaging cos site and encoding rhamnose-inducible P4 delta and epsilon genes. It also has tail fiber (H) and its chaperone (G) deleted.

Antibodies from Article