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ALS Variants of Annexin A11's Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution.

Shihora A, Elias RD, Hammond JA, Ghirlando R, Deshmukh L
ACS Chem Neurosci. 2023 Jul 11. doi: 10.1021/acschemneuro.3c00169. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
196208GB1-A11(2-196)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-196)-Strep.
196209GB1-A11(2-196, G38R)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-196, G38R)-Strep.
196210GB1-A11(2-196, D40G)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-196, D40G)-Strep.
196211GB1-A11(2-196, G175R)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-196, G175R)-Strep.
196212GB1-A11(2-196, G189E)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-196, G189E)-Strep.
196213GB1-A11(2-52)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-52)-Strep.
196214GB1-A11(2-88)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-88)-Strep.
196215GB1-A11(89-196)Codon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(89-196).
196216GB1-A11(2-68)-StrepCodon-optimized bacterial expression plasmid. Expresses GB1-His6-TEV-A11(2-68)-Strep.
196217S100A6Codon-optimized bacterial expression plasmid. Expresses S100A6.

Antibodies from Article