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A genome-wide genetic screen uncovers determinants of human pigmentation.
Bajpai VK, Swigut T, Mohammed J, Naqvi S, Arreola M, Tycko J, Kim TC, Pritchard JK, Bassik MC, Wysocka J
Science. 2023 Aug 11;381(6658):eade6289. doi: 10.1126/science.ade6289. Epub 2023 Aug 11. PubMed Article

Plasmids from Article

ID Plasmid Purpose
195506Pb-TRE3G-SpCas9-IRES-blastInducible Piggybac vector expressing SpCas9 with Blasticidin selection
195507Pb459-mU6-sgRNA-EF1a-PuroRpiggybac vector expressing non-targeting control sgRNA cloned using BlpI and BstXI sites
195508Pb-TRE3G-TYR-HygRinducible Piggybac vector expressing human TYR CDS with hygromycin selection
195509pCHA1.1-COMMD3_CDS-V5-hygrolentiviral vector expressing COMMD3 CDS with hygromycin selection
195510pCHA1.1-Rap2a-V5-Hygrolentiviral vector expressing RAP2A CDS with hygromycin selection

Antibodies from Article