Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes.

Ge Y, Onengut-Gumuscu S, Quinlan AR, Mackey AJ, Wright JA, Buckner JH, Habib T, Rich SS, Concannon P
Diabetes. 2016 Mar;65(3):794-802. doi: 10.2337/db15-0322. Epub 2015 Dec 2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
195375	FLAG-Ex1-17-PTPN22	Mammalian expression of a human PTPN22 mutant (exon 1-17) with FLAG tag
195377	pDONR221-In18runon-PTPN22	A human PTPN22 mutant (intron 18-runon) in Gateway pDONR221
195379	FLAG-In18runon-PTPN22	Mammalian expression of a human PTPN22 mutant (intron 18-runon) with FLAG tag