Ras drives malignancy through stem cell crosstalk with the microenvironment.
Yuan S, Stewart KS, Yang Y, Abdusselamoglu MD, Parigi SM, Feinberg TY, Tumaneng K, Yang H, Levorse JM, Polak L, Ng D, Fuchs E
Nature. 2022 Nov 30. doi: 10.1038/s41586-022-05475-6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 195332 | SBE-NLS-mCherry PGK-rtTA3 | Lentiviral construct of TGFβ reporter (nuclear mCherry) and hPGK driven rtTA3 |
| 195881 | TRE-VEGFA EF1a-rtTA3 | Lentiviral construct of doxycycline inducible VEGFA |
| 195882 | TRE-STOP EF1a-rtTA3 | control construct of TRE-VEGFA EF1a-rtTA3 |
| 195883 | hPGK-rtTA3 | Lentiviral construct of hPGK driven rtTA3 |
| 196584 | Lepr peak reporter-eGFP | Cis-regulatory region of mouse Lepr gene driven a eGFP reporter with hGFP driven rtTA3 |
| 196635 | TRE-Lepr_FL-IRES-eGFP | Doxycycline inducible expression of full length mouse Lepr with eGFP marker |
| 196935 | TRE-Lepr_Short-IRES-eGFP | Doxycycline inducible expression of short Lepr (no signaling) with eGFP marker |