A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.

Vizoso M, E J Pritchard C, Bombardelli L, van den Broek B, Krimpenfort P, Beijersbergen RL, Jalink K, van Rheenen J
Nat Commun. 2022 Oct 28;13(1):6442. doi: 10.1038/s41467-022-33863-z. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

Showing 1 to 3 of 3 entries

Show entries

Search table:

ID	Plasmid	Purpose
200191	UbC-blasticidine-P2A-TETon-3G transactivator	A TETon activator, which combined with the DiLiCre 2.0 plasmid, drives the expression of DiLiCre 2.0 upon doxycycline. DiLiCre 2.0 is a cre recombinase that is activated by violet light.
198753	EF1α-Lox2272-LoxP-MARKS·mTurquoise2-NLS·turboRFP-Lox2272-LoxP	Cre reporter, which switches from membraneous mTurquoise to nuclear RFP upon Cre recombinase activity
198752	DiLiCre 2.0	A Cre recombinase that is expressed upon doxycycline when combined with the UbC-blasticidine-P2A-TETon-3G transactivator. DiLiCre 2.0 is a cre recombinase that is activated by violet light.