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De novo design of luciferases using deep learning.

Yeh AH, Norn C, Kipnis Y, Tischer D, Pellock SJ, Evans D, Ma P, Lee GR, Zhang JZ, Anishchenko I, Coventry B, Cao L, Dauparas J, Halabiya S, DeWitt M, Carter L, Houk KN, Baker D
Nature. 2023 Feb;614(7949):774-780. doi: 10.1038/s41586-023-05696-3. Epub 2023 Feb 22. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
194299pET29_LuxSit_iBacterial expression of the de novo luciferase, LuxSit-i
194300pCDNA3_LuxSit_i_mTagBFP2Mammalian expression of the de novo luciferase, LuxSit-i

Antibodies from Article