Pleiotropic effects of laminar flow and statins depend on the Kruppel-like factor-induced lncRNA MANTIS.
Leisegang MS, Bibli SI, Gunther S, Pfluger-Muller B, Oo JA, Hoper C, Seredinski S, Yekelchyk M, Schmitz-Rixen T, Schurmann C, Hu J, Looso M, Sigala F, Boon RA, Fleming I, Brandes RP
Eur Heart J. 2019 Aug 7;40(30):2523-2533. doi: 10.1093/eurheartj/ehz393.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 194187 | pGL3-pSMANTIS_WT_1kb | Includes the promoter (1kb) of SMTS (SMANTIS, MANTIS, AK125871) |
| 194188 | pGL3-pSMANTIS_SMAD-FOS_Mutant | Includes the promoter (1kb) of SMTS with mutated SMAD/FOS binding site |
| 194189 | pGL3-pSMANTIS_STAT1-2_Mutant | Includes the promoter (1kb) of SMTS with mutated STAT1/2 binding site |
| 194190 | pGL3-pSMANTIS_1kb_KLF2mut 449,548,732,899,884 (All) | Includes the promoter (1kb) of SMTS with 5 mutated KLF binding sites (positions 449,548,732,899,884) |
| 194191 | pGL3-pSMANTIS_1kb_KLF2mut 449,548,732,899 (Quin) | Includes the promoter (1kb) of SMTS with 4 mutated KLF binding sites (positions 449,548,732,899) |
| 194192 | pGL3-pSMANTIS_1kb_KLF2mut 449,548,732 (Tri) | Includes the promoter (1kb) of SMTS with 3 mutated KLF binding sites (positions 449,548,732) |
| 194193 | pGL3-pSMANTIS_1kb_KLF2mut 899 | Includes the promoter (1kb) of SMTS with mutated KLF binding sites (position 899) |
| 194194 | pGL3-pSMANTIS_1kb_KLF2mut 548 | Includes the promoter (1kb) of SMTS with mutated KLF binding sites (position 548) |
| 194195 | pGL3-pSMANTIS_1kb_KLF2mut 732 | Includes the promoter (1kb) of SMTS with mutated KLF binding sites (position 732) |
| 194196 | pGL3-pSMANTIS_1kb_KLF2mut 884 | Includes the promoter (1kb) of SMTS with mutated KLF binding sites (position 884) |
| 194197 | pGL3-pSMANTIS_1kb_KLF2mut 449 | Includes the promoter (1kb) of SMTS with mutated KLF binding sites (position 449) |