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Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer.

Barger CJ, Suwala AK, Soczek KM, Wang AS, Kim MY, Hong C, Doudna JA, Chang SM, Phillips JJ, Solomon DA, Costello JF
Nat Commun. 2022 Sep 16;13(1):5430. doi: 10.1038/s41467-022-33099-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
193785pGL4.0-TERT_-100_-79luciferase reporter for duplicated TERT promoter

Antibodies from Article