Lysosomal positioning regulates Rab10 phosphorylation at LRRK2(+) lysosomes.
Kluss JH, Beilina A, Williamson CD, Lewis PA, Cookson MR, Bonet-Ponce L
Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2205492119. doi: 10.1073/pnas.2205492119. Epub 2022 Oct 18.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
193582 | LYSO-LRRK2 | Expresses human full-length LRRK2 with a lysosomal targeting sequence from LAMTOR1 (1-39aa) and 3xFLAG on the N-terminus |
193583 | EE-LRRK2 | Expresses full-length LRRK2 with FYVE-CC2 domains from HRS and 3xFLAG on the N-terminus |
193584 | 3xFLAG-FKBP-LRRK2 | Expresses human full-length LRRK2 with FKBP domain and 3xFLAG situated at the N-terminus |