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Improved cytosine base editors generated from TadA variants.

Lam DK, Feliciano PR, Arif A, Bohnuud T, Fernandez TP, Gehrke JM, Grayson P, Lee KD, Ortega MA, Sawyer C, Schwaegerle ND, Peraro L, Young L, Lee SJ, Ciaramella G, Gaudelli NM
Nat Biotechnol. 2023 Jan 9. doi: 10.1038/s41587-022-01611-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
193258CABE-T1.2Expression of CABE-T1.2 base editor in mammalian cells, CMV promoter
193259CABE-T1.14Expression of CABE-T1.14 base editor in mammalian cells, CMV promoter
193260CABE-T1.17Expression of CABE-T1.17 base editor in mammalian cells, CMV promoter
193261CABE-T1.19Expression of CABE-T1.19 base editor in mammalian cells, CMV promoter
193262CABE-T2.5Expression of CABE-T2.5 base editor in mammalian cells, CMV promoter
193263CABE-T2.6Expression of CABE-T2.6 base editor in mammalian cells, CMV promoter
193264CABE-T2.9Expression of CABE-T2.9 base editor in mammalian cells, CMV promoter
193265CABE-T2.19Expression of CABE-T2.19 base editor in mammalian cells, CMV promoter
193266CABE-T2.23Expression of CABE-T2.23 base editor in mammalian cells, CMV promoter
193267CABE-T3.1Expression of CABE-T3.1 base editor in mammalian cells, CMV promoter
193268CABE-T3.153Expression of CABE-T3.153 base editor in mammalian cells, CMV promoter
193269CABE-T3.154Expression of CABE-T3.154 base editor in mammalian cells, CMV promoter
193270CABE-T3.155Expression of CABE-T3.155 base editor in mammalian cells, CMV promoter
193271CBE-T1.2Expression of CBE-T1.2 base editor in mammalian cells, CMV promoter
193272CBE-T1.3Expression of CBE-T1.3 base editor in mammalian cells, CMV promoter
193273CBE-T1.4Expression of CBE-T1.4 base editor in mammalian cells, CMV promoter
193274CBE-T1.5Expression of CBE-T1.5 base editor in mammalian cells, CMV promoter
193275CBE-T1.6Expression of CBE-T1.6 base editor in mammalian cells, CMV promoter
193276CBE-T1.13Expression of CBE-T1.13 base editor in mammalian cells, CMV promoter
193277CBE-T1.14Expression of CBE-T1.14 base editor in mammalian cells, CMV promoter
193278CBE-T1.21Expression of CBE-T1.21 base editor in mammalian cells, CMV promoter
193279CBE-T1.28Expression of CBE-T1.28 base editor in mammalian cells, CMV promoter
193280CBE-T1.30Expression of CBE-T1.30 base editor in mammalian cells, CMV promoter
193281CBE-T1.31Expression of CBE-T1.31 base editor in mammalian cells, CMV promoter
193282CBE-T1.32Expression of CBE-T1.32 base editor in mammalian cells, CMV promoter
193283CBE-T1.45Expression of CBE-T1.45 base editor in mammalian cells, CMV promoter
193284CBE-T1.46Expression of CBE-T1.46 base editor in mammalian cells, CMV promoter
193285CBE-T1.52Expression of CBE-T1.52 base editor in mammalian cells, CMV promoter
193286CBE-T1.53Expression of CBE-T1.53 base editor in mammalian cells, CMV promoter

Antibodies from Article