A multiplexed in vivo approach to identify driver genes in small cell lung cancer.
Lee MC, Cai H, Murray CW, Li C, Shue YT, Andrejka L, He AL, Holzem AME, Drainas AP, Ko JH, Coles GL, Kong C, Zhu S, Zhu C, Wang J, van de Rijn M, Petrov DA, Winslow MM, Sage J
Cell Rep. 2023 Jan 13;42(1):111990. doi: 10.1016/j.celrep.2023.111990.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 193198 | Lenti-EFS-EGFP-T2A-Bsd | Lentiviral vector expressing EGFP (driven by EFS promoter) and a blasticidin resistance marker |
| 193199 | Lenti-EFS-hTSC1-T2A-Bsd | Lentiviral vector expressing human TSC1 cDNA (driven by EFS promoter) and a blasticidin resistance marker |
| 193200 | Lenti-sgAdgb#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Adgb gene |
| 193201 | Lenti-sgAdgb#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Adgb gene |
| 193202 | Lenti-sgApc#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Apc gene |
| 193203 | Lenti-sgBrip1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Brip1 gene |
| 193204 | Lenti-sgBrip1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Brip1 gene |
| 193205 | Lenti-sgCol11a1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Col11a1 gene |
| 193206 | Lenti-sgCol11a1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Col11a1 gene |
| 193207 | Lenti-sgCol22a1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Col22a1 gene |
| 193208 | Lenti-sgCol22a1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Col22a1 gene |
| 193209 | Lenti-sgCrebbp#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Crebbp gene |
| 193210 | Lenti-sgCrebbp#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Crebbp gene |
| 193211 | Lenti-sgErich3#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Erich3 gene |
| 193212 | Lenti-sgErich3#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Erich3 gene |
| 193213 | Lenti-sgFam135b#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Fam135b gene |
| 193214 | Lenti-sgFam135b#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Fam135b gene |
| 193215 | Lenti-sgFlt4#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Flt4 gene |
| 193216 | Lenti-sgFlt4#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Flt4 gene |
| 193217 | Lenti-sgGrin2a#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Grin2a gene |
| 193218 | Lenti-sgHcn1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Hcn1 gene |
| 193219 | Lenti-sgMroh2b#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Mroh2b gene |
| 193220 | Lenti-sgMroh2b#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Mroh2b gene |
| 193221 | Lenti-sgNkx2-1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Nkx2-1 gene |
| 193222 | Lenti-sgNkx2-1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Nkx2-1 gene |
| 193223 | Lenti-sgNotch1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch1 gene |
| 193224 | Lenti-sgNotch1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch1 gene |
| 193225 | Lenti-sgNotch2#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch2 gene |
| 193226 | Lenti-sgNotch2#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch2 gene |
| 193227 | Lenti-sgNotch3#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch3 gene |
| 193228 | Lenti-sgNotch3#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Notch3 gene |
| 193229 | Lenti-sgPcdh15#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Pcdh15 gene |
| 193230 | Lenti-sgPcdh15#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Pcdh15 gene |
| 193231 | Lenti-sgPrdm9#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Prdm9 gene |
| 193232 | Lenti-sgPrdm9#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Prdm9 gene |
| 193233 | Lenti-sgRos1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Ros1 gene |
| 193234 | Lenti-sgRos1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Ros1 gene |
| 193235 | Lenti-sgRunx1t1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Runx1t1 gene |
| 193236 | Lenti-sgRunx1t1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Runx1t1 gene |
| 193237 | Lenti-sgSis#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Sis gene |
| 193238 | Lenti-sgSis#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Sis gene |
| 193239 | Lenti-sgSpen#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Spen gene |
| 193240 | Lenti-sgSpen#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Spen gene |
| 193241 | Lenti-sgSphkap#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Sphkap gene |
| 193242 | Lenti-sgTmem132d#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Tmem132d gene |
| 193243 | Lenti-sgTmem132d#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Tmem132d gene |
| 193244 | Lenti-sgTnr#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Tnr gene |
| 193245 | Lenti-sgTnr#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Tnr gene |
| 193246 | Lenti-sgTsc1#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Tsc1 gene |
| 193247 | Lenti-sgTsc1#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Tsc1 gene |
| 193248 | Lenti-sgZfp536#1/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Zfp536 gene |
| 193249 | Lenti-sgZfp536#2/Cre | Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Zfp536 gene |