DNA methylation-independent long-term epigenetic silencing with dCRISPR/Cas9 fusion proteins.
Ding L, Schmitt LT, Brux M, Surun D, Augsburg M, Lansing F, Mircetic J, Theis M, Buchholz F
Life Sci Alliance. 2022 Mar 14;5(6). pii: 5/6/e202101321. doi: 10.26508/lsa.202101321. Print 2022 Jun.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 220143 | PB-TRE-dCas9-Zim3-MeCP2 | doxycycline-inducible dCas9-Zim3-MeCP2 expression for Epigenetic repression |