Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

HP1alpha is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics.

Strom AR, Biggs RJ, Banigan EJ, Wang X, Chiu K, Herman C, Collado J, Yue F, Ritland Politz JC, Tait LJ, Scalzo D, Telling A, Groudine M, Brangwynne CP, Marko JF, Stephens AD
Elife. 2021 Jun 9;10. pii: 63972. doi: 10.7554/eLife.63972. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
127906Human 3' HP1a AID GFP PuroRHDR (donor) Plasmid for Inserting AID-GFP-2A-Puro into the 3' end of the Human HP1a Gene
127907pX330 Human 3' HP1a gRNAWT Cas9 Vector targeting the 3' end of the human HP1a gene
127909SB100X in pCAG globin pASleeping Beauty Transposase expression vector driven by the CAG promoter
127910pEf1a OsTIR ires NEO pA T2BHTransposon vector containing an OsTIR IRES Neo cassette driven by the Ef1a promoter

Antibodies from Article