Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies.
Hanke L, Sheward DJ, Pankow A, Vidakovics LP, Karl V, Kim C, Urgard E, Smith NL, Astorga-Wells J, Ekstrom S, Coquet JM, McInerney GM, Murrell B
Sci Adv. 2022 Mar 25;8(12):eabm0220. doi: 10.1126/sciadv.abm0220. Epub 2022 Mar 25.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 194589 | pHEN-CoV2-nanobody-G6 | Bacterial expression of G6 nanobody targeting the receptor binding domain (RBD) of SARS-CoV-2 spike |
| 194590 | pHEN-CoV2-nanobody-E2 | Bacterial expression of E2 nanobody targeting the receptor binding domain (RBD) of SARS-CoV-2 spike |
| 194591 | pHEN-CoV2-nanobody-C7 | Bacterial expression of C7 nanobody targeting the receptor binding domain (RBD) of SARS-CoV-2 spike |
| 194592 | pHEN-CoV2-nanobody-F1 | Bacterial expression of F1 nanobody targeting the receptor binding domain (RBD) of SARS-CoV-2 spike |