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Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing.

Rodriguez-Rozada S, Wietek J, Tenedini F, Sauter K, Dhiman N, Hegemann P, Soba P, Wiegert JS
Commun Biol. 2022 Jul 9;5(1):687. doi: 10.1038/s42003-022-03636-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
192569hSyn-Aion-citrineAAV-vector for optogenetic long-term silencing of neurons
192570hSyn-somAion-citrineAAV-vector for optogenetic long-term silencing of neurons
192575hSyn-Aion-ts-citrine-ERAAV-vector for optogenetic long-term silencing of neurons

Antibodies from Article