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Revealing beta-TrCP activity dynamics in live cells with a genetically encoded biosensor.

Paul D, Kales SC, Cornwell JA, Afifi MM, Rai G, Zakharov A, Simeonov A, Cappell SD
Nat Commun. 2022 Oct 26;13(1):6364. doi: 10.1038/s41467-022-33762-3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
192458betaTrCP mVenus reporterFluorescent reporter for beta-TrCP activity in human cells
192459betaTrCP mVenus mutant reporterFluorescent reporter for beta-TrCP with a non-degradable mutation. Used as a control.

Antibodies from Article