Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.
Wang G, Chow RD, Bai Z, Zhu L, Errami Y, Dai X, Dong MB, Ye L, Zhang X, Renauer PA, Park JJ, Shen L, Ye H, Fuchs CS, Chen S
Nat Immunol. 2019 Nov;20(11):1494-1505. doi: 10.1038/s41590-019-0500-4. Epub 2019 Oct 14.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 192159 | pGW05 AAV-CRISPRa base vector pAAV-OE_U6-Lib(MS2)-EF1a-MPH-sPA | AAV-CRISPRa base vector |
| 192160 | pGW011b Dual AAV vector pAAV-EFS-dCAS9-spA | Dual AAV vector AAV-dCas9 |
| 192161 | pGW045 AAV-CRISPRa base vector pAAV_OE-U6sgbbSapI(MS2)-EF1a-MPH-WPRE | AAV-CRISPRa base vector |