In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma.
Ye L, Park JJ, Dong MB, Yang Q, Chow RD, Peng L, Du Y, Guo J, Dai X, Wang G, Errami Y, Chen S
Nat Biotechnol. 2019 Nov;37(11):1302-1313. doi: 10.1038/s41587-019-0246-4. Epub 2019 Sep 23.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 192151 | pLY017SB_pAAV-U6sg(BbsI)-EFS-Thy1.1-P2A-SB100X | T cell CRISPR AAV-SB vector |