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High-performance multiplex drug-gated CAR circuits.

Li HS, Wong NM, Tague E, Ngo JT, Khalil AS, Wong WW
Cancer Cell. 2022 Aug 26. pii: S1535-6108(22)00372-5. doi: 10.1016/j.ccell.2022.08.008. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
192115pHR-Traditional CAR (anti-CD19)Lentiviral delivery of Traditional CAR(anti-CD19)
192117pHR-ON VIPER CAR (anti-CD19)-final designLentiviral deliviery of ON VIPER CAR (anti-CD19)-final design
192122pHR-OFF VIPER CAR (anti-CD19)-candidate (c+iii)Lentiviral deliviery of OFF VIPER CAR (anti-CD19)-candidate design(c+iii)
192123pHR-OFF VIPER CAR (anti-CD19)-candidate design(d+i)Lentiviral deliviery of OFF VIPER CAR (anti-CD19)-candidate design(d+i)
192124pHR-OFF VIPER CAR (anti-CD19)-candidate design(d+iii)pHR-OFF VIPER CAR (anti-CD19)-candidate design(d+iii)

Antibodies from Article