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Extracellular regulated kinase phosphorylates mitofusin 1 to control mitochondrial morphology and apoptosis.

Pyakurel A, Savoia C, Hess D, Scorrano L
Mol Cell. 2015 Apr 16;58(2):244-54. doi: 10.1016/j.molcel.2015.02.021. Epub 2015 Mar 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
191976p3xFLAG-CMV-14-Mfn1-T562ATo produce mutants mimicking dephosphorylated Mfn1
191977p3xFLAG-CMV-14-Mfn1-T562DTo produce mutants mimicking phosphorylated Mfn1
191978p3xFLAG-CMV-14-Mfn1-T564ATo produce mutants mimicking dephosphorylated Mfn1
191979p3xFLAG-CMV-14-Mfn1-T564DTo produce mutants mimicking phosphorylated Mfn1

Antibodies from Article