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Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria.

Cereghetti GM, Stangherlin A, Martins de Brito O, Chang CR, Blackstone C, Bernardi P, Scorrano L
Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15803-8. doi: 10.1073/pnas.0808249105. Epub 2008 Oct 6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
191965pcDNA3.1/Zeo-CnBExpression of CnB (calcineurin subunit beta).
191966pcDNA3.1/Zeo-CnAExpression of CnA (calcineurin subunit alpha)
191967pcDNA3.1/Zeo-CnA-H151QExpression of dominant negative CnA H151Q mutant protein (catalytically inactive).

Antibodies from Article