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DNA processing by the Kaposi's sarcoma-associated herpesvirus alkaline exonuclease SOX contributes to viral gene expression and infectious virion production.

Hartenian E, Mendez AS, Didychuk AL, Khosla S, Glaunsinger BA
Nucleic Acids Res. 2023 Jan 11;51(1):182-197. doi: 10.1093/nar/gkac1190. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
191657pMDC Renilla Luc SREExpressed Renilla Luciferase with SOX resistance element
192049pACE WT SOX pACEmam1Expresses WT SOX (pACEmam1)
192050SOX D221A/E244A/K246A pACEmam1Expresses a 3X catalytic mutant of SOX (ORF37)
192051pACE SOX (ORF37) K246AExpresses a catalytic mutant of SOX (K246A)
192052pACE SOX (ORF37) K250AExpresses a DNA binding mutant K250A (ORF37)
192053pACE SOX (ORF37) D221N E244QExpresses a 2X catalytic mutant of (ORF37) D221N E244Q
192054pACE SOX (ORF37) 318-320AExpresses a mutant of SOX 318-320A
192055pFastBac WT SOXExpression vector for WT SOX
192057pFastBac SOX Q129HExpression vector for SOX (ORF37) Q129H
192058pFastBac SOX R139AExpression vector for SOX (ORF37) R139A
192060pFastBac SOX 318-320AExpression vector for SOX (ORF37) 318-320A

Antibodies from Article