Epistatic effects between amino acid insertions and substitutions mediate toxin-resistance of vertebrate Na+, K+-ATPases.
Mohammadi S, Ozdemir HI, Ozbek P, Sumbul F, Stiller J, Deng Y, Crawford AJ, Rowland HM, Storz JF, Andolfatto P, Dobler S
Mol Biol Evol. 2022 Dec 6:msac258. doi: 10.1093/molbev/msac258.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 191226 | Chinchilla–insM | Expresses Na,K-ATPase (ATP1A1 and ATP1B1 in pFastBac Dual vector) in insect cells |
| 191227 | Chinchilla+N122D–insM | Expresses Na,K-ATPase (ATP1A1 and ATP1B1 in pFastBac Dual vector) in insect cells |
| 191228 | Sandgrouse–insD | Expresses Na,K-ATPase (ATP1A1 and ATP1B1 in pFastBac Dual vector) in insect cells |
| 191229 | Sandgrouse+R111Q–insD | Expresses Na,K-ATPase (ATP1A1 and ATP1B1 in pFastBac Dual vector) in insect cells |