A simplified function-first method for the discovery and optimization of bispecific immune engaging antibodies.
Shepherd A, Bennychen B, Marcil A, Bloemberg D, Pon RA, Weeratna RD, McComb S
PLoS One. 2023 Jun 22;18(6):e0273884. doi: 10.1371/journal.pone.0273884. eCollection 2023.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 190677 | pBITE-CD19-CD3 | Encodes a modularized form of HD37-OKT3 bispecific antibody |
| 190679 | pBITE-EGFRvIII-F265-OKT3 | Encodes an EGFRvIII-CD3 BITE protein (F265 clone) |
| 190680 | pBITE-EGFRvIII-F263-OKT3 | Encodes an EGFRvIII-CD3 BITE protein (F263 clone) |
| 190681 | pBITE-EGFRvIII-F269-OKT3 | Encodes an EGFRvIII-CD3 BITE protein (F269 clone) |
| 190682 | pBITE-EGFRvIII-F271-OKT3 | Encodes an EGFRvIII-CD3 BITE protein (F271 clone) |