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Spike recognition and neutralization of SARS-CoV-2 Omicron subvariants elicited after the third dose of mRNA vaccine.

Tauzin A, Nicolas A, Ding S, Benlarbi M, Medjahed H, Chatterjee D, Dionne K, Gong SY, Gendron-Lepage G, Bo Y, Perreault J, Goyette G, Gokool L, Arlotto P, Morrisseau C, Tremblay C, Martel-Laferriere V, De Serres G, Levade I, Kaufmann DE, Cote M, Bazin R, Finzi A
Cell Rep. 2023 Jan 31;42(1):111998. doi: 10.1016/j.celrep.2023.111998. Epub 2023 Jan 9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
186031pCAGGS SARS-CoV-2 BA.4/5 SpikeExpresses codon-optimized full length SARS-CoV-2 BA.4/5 Spike
190012pCAGGS SARS-CoV-2 BA.2.75 SpikeExpresses codon-optimized full length SARS-CoV-2 BA.2.75 Spike
190013pCAGGS SARS-CoV-2 BA.4.6 SpikeExpresses codon-optimized full length SARS-CoV-2 BA.4.6 Spike
193710pCAGGS SARS-CoV-2 BQ.1.1 SpikeExpresses codon-optimized full length SARS-CoV-2 BQ.1.1 Spike

Antibodies from Article