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Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice.

Brilkova M, Nigri M, Kumar HS, Moore J, Mantovani M, Keller C, Grimm A, Eckert A, Shcherbakov D, Akbergenov R, Seebeck P, Kramer SD, Wolfer DP, Gent TC, Bottger EC
Cell Rep. 2022 Sep 27;40(13):111433. doi: 10.1016/j.celrep.2022.111433. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
190271pRps9-WT-IRES-GFP-HygRExpress RPS9 WT mouse gene transcriptionally fused with eGFP. eGFP is translated from IRES.
190272pRps9-D95N-IRES-GFP-HygRExpress RPS9 D95N-mutant mouse gene transcriptionally fused with eGFP. eGFP is translated from IRES.

Antibodies from Article