A transthyretin monomer intermediate undergoes local unfolding and transient interaction with oligomers in a kinetically concerted aggregation pathway.
Sun X, Ferguson JA, Dyson HJ, Wright PE
J Biol Chem. 2022 Jun 18;298(8):102162. doi: 10.1016/j.jbc.2022.102162.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
190008 | TTR C10S S46C | Expression of human TTR in E coli |
190009 | TTR C10S E63C | Expression of human TTR in E coli |
190010 | TTR C10S S100C | Expression of human TTR in E coli |