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Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins.

Berlow RB, Dyson HJ, Wright PE
Proc Natl Acad Sci U S A. 2022 Jan 18;119(3). pii: 2117338119. doi: 10.1073/pnas.2117338119. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
189961HisGB1-CITED(216-242)+CBPTAZ1(340-439)Coexpression of CBP TAZ1 and CITED in E coli
189962H6Gb1-CITED2(216-246)+CBP TAZ1(340-439)Expression of CBP TAZ1 and CITED2 in E coli
189963H6GB1-CITED2(216-269APAA) + CBP TAZ1(340-439)Coexpression of CBP TAZ1 and CITED2 in E coli

Antibodies from Article