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Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.

Kwon JJ, Hajian B, Bian Y, Young LC, Amor AJ, Fuller JR, Fraley CV, Sykes AM, So J, Pan J, Baker L, Lee SJ, Wheeler DB, Mayhew DL, Persky NS, Yang X, Root DE, Barsotti AM, Stamford AW, Perry CK, Burgin A, McCormick F, Lemke CT, Hahn WC, Aguirre AJ
Nature. 2022 Jul 13. pii: 10.1038/s41586-022-04928-2. doi: 10.1038/s41586-022-04928-2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
190568plx307 SHOC2 V5 WTSHOC2 variant overexpression
190569plx307 SHOC2 WT G63RSHOC2 variant overexpression
190570plx307 SHOC2 V5 Q249KSHOC2 variant overexpression
190571plx307 SHOC2 V5 F66VSHOC2 variant overexpression
190572plx307 SHOC2 V5 E457KSHOC2 variant overexpression
190573plx307 SHOC2 V5 Y131ESHOC2 variant overexpression
190574plx307 SHOC2 V5 M173ISHOC2 variant overexpression
190575plx307 SHOC2 V5 M173VSHOC2 variant overexpression
190576plx307 SHOC2 V5 R223FSHOC2 variant overexpression
190577plx307 SHOC2 V5 T411ASHOC2 variant overexpression
190578plx307 SHOC2 V5 V64GSHOC2 variant overexpression
190579plx307 SHOC2V5 N434DSHOC2 variant overexpression
190580plx307 SHOC2 V5 R182ESHOC2 variant overexpression
190581plx307 SHOC2 V5 M219VSHOC2 variant overexpression

Antibodies from Article