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Engineering of near-PAMless adenine base editor with enhanced editing activity and reduced off-target.

Cao X, Guo J, Huang S, Yu W, Li G, An L, Li X, Tao W, Liu Q, Huang X, Jin X, Ma X
Mol Ther Nucleic Acids. 2022 May 4;28:732-742. doi: 10.1016/j.omtn.2022.04.032. eCollection 2022 Jun 14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
188913CE-8e-SpRYA-to-G base editor

Antibodies from Article