Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry.
Kastenhuber ER, Mercadante M, Nilsson-Payant B, Johnson JL, Jaimes JA, Muecksch F, Weisblum Y, Bram Y, Chandar V, Whittaker GR, tenOever BR, Schwartz RE, Cantley L
Elife. 2022 Mar 23;11. pii: 77444. doi: 10.7554/eLife.77444.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
187482 | pEGPN | Expression vector - GFP |
187483 | pEGPN-ACE2 | Expression vector - ACE2 |
187484 | pEGPN-TMPRSS2 | Expression vector - TMPRSS2 |