Telomerase inhibition is an effective therapeutic strategy in TERT promoter-mutant glioblastoma models with low tumor volume.
Aquilanti E, Kageler L, Watson J, Baird DM, Jones RE, Hodges M, Szegletes ZM, Doench JG, Strathdee CA, Figueroa JRMF, Ligon KL, Beck M, Wen PY, Meyerson M
Neuro Oncol. 2023 Jul 6;25(7):1275-1285. doi: 10.1093/neuonc/noad024.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 187159 | pRDA_355 | Lentiviral expression of doxycycline inducible customizable Sp Cas9 sgRNA |