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Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability.

Unlu G, Prizer B, Erdal R, Yeh HW, Bayraktar EC, Birsoy K
Mol Cell. 2022 Aug 4;82(15):2832-2843.e7. doi: 10.1016/j.molcel.2022.05.024. Epub 2022 Jun 16. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
187080Human Metabolic Gene CRISPRa sgRNA libraryLentiviral CRISPRa library targeting human metabolic genes for activation of gene expression
187081Mouse Metabolic Gene CRISPRa sgRNA libraryLentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

Antibodies from Article