A synergy between mechanosensitive calcium- and membrane-binding mediates tension-sensing by C2-like domains.

Shen Z, Belcheva KT, Jelcic M, Hui KL, Katikaneni A, Niethammer P
Proc Natl Acad Sci U S A. 2022 Jan 4;119(1). pii: 2112390119. doi: 10.1073/pnas.2112390119. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
187001	Phat2-dr-cPla2-C2-EGFP-6H	Protein Expression
187088	Phat2-hs-cPla2-C2-EGFP-GH	Protein Expression
187104	Phat2-dr-cPla2-C2-mCherry-6H	Protein Expression
187113	pGEX-6P-1-hs-ALPS 1-ALPS2-EGFP	Protein Expression
187114	pGEX-6P-1-hs-ALPS 1-ALPS2-mCherry	Protein Expression
187115	Phat2-hs-PKCgamma-C2-EGFP-6H	Protein Expression
187157	Phat2-hs-AKT1-PH-EGFP-6H	Protein Expression
187183	Phat2-dr-cPla2-C2-L32A-L33A-EGFP-6H	Protein Expression
187184	Phat2-dr-cPla2-C2-L32F-L33F-EGFP-6H	Protein Expression
187185	Phat2-dr-cPla2-C2-Y90A-V91A-EGFP-6H	Protein Expression
187186	Phat2-dr-cPla2-C2-Y90F-V91F-EGFP-6H	Protein Expression
187187	Phat2-dr-cPla2-C2-D34K-D87K-EGFP-6H	Protein Expression
187188	Phat2-dr-cPla2-C2-D34R-D87R-EGFP-6H	Protein Expression
187189	Phat2-dr-Alox5-PLAT-EGFP-6H	Protein Expression
187190	Phat2-dr-Alox12-PLAT-EGFP-6H	Protein Expression

Antibodies from Article